FDA Issues Alert for Pregnant Women Taking Diflucan

by Pregnancy.org Staff

In the news: Pregnant women taking high doses of Diflucan face a risk of a rare birth defect in their infants according to the FDA.

The U.S. Food and Drug Administration issued a notice that, "treatment during the first trimester of pregnancy with high doses of 400 to 800 mg per day of Diflucan, also known as Fluconazole, may be associated with a rare birth defect in infants." A single, low dose of 150 mg to treat vaginal yeast infection does not appear to carry the risk however.

Patients are being asked to tell their healthcare professionals if they are or become pregnant while taking Fluconazole. The medication is prescribed for yeast infections of the vagina, mouth, throat, esophagus and other organs according to the FDA. It's commonly used to prevent yeast infections in patients, "prone to infection because of chemotherapy or radiation therapy before a bone marrow transplant, and to treat meningitis caused by a certain type of fungus."

Doctors and patients are being told to report adverse events or side-effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program at www.fda.gov/MedWatch/report.htm, or by calling (800) 332-1088 to request a reporting form.

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