This is mostly for PedNurse, but also I hope anyone else lurking who has gone through recurrent loss might benefit from others' experiences. Obviously I'm not a doctor, and I'm sure this is not going to be a full list, but this is what I remember. Anyone else who has been through testing, please feel free to comment and add in. Again, this is not medical advice as I am not a doctor, this list is just meant to be a place to start a conversation with your doctor if you are not sure what you can ask for (although hopefully your doctor should know...)
PedNurse, I completely agree with Bonita that I don't see why you should have to wait for "next time" for most of these, and that I hope your doctor is open to and knowledgeable about different causes of recurrent miscarriage.
1. Genetic - As you mentioned, there are different types of genetic screenings. I don't know what all of them are, but the one that I know of that may possible cause recurrent loss is a MTHFR mutation. I have this. The thing that it does is make it harder for your body to process folic acid, which is really important to developing new tissue including new babies. The treatment for this is pretty benign - extra folic acid and vitB. I'm sure there are all sorts of other genetic tests they do, I just don't know what they are.
2. Structural - Not sure if they can do this one while you're actually pregnant, but at some point they can do what is called a Hysterosalpingogram (HSG) which is basically where they shoot radioactive dye into your uterus, take an MRI, and look for any sorts of structural abnormalities that could be causing problems.
3. Blood tests - They can check your thyroid levels (thyroid problems can wreak havoc with pregnancy), as well as possible blood clotting issues that may be treated with baby aspirin or possibly low molecular weight heparin.
4. Betas - Testing for progesterone levels is a big one. Low progesterone seems to be a common theme in miscarriages, and is easy to fix with either an oral pill or suppository.
5. Bacterial - There are certain types of bacteria that can live on your cervix that seem to be implicated in recurrent loss. If found, these can be treated with antibiotics.
Those are all of the ones that I can think of, but again, your doctor should know a heck of a lot more than I do...lol The good news is that almost all of these issues are treatable (genetic issues aren't "curable", as we can't change our genes, but may be treatable as in my case where I simply need to take a buttload more folic acid.)
I hope this is helpful, and anyone else out there that has been through testing, please feel free to add/correct and otherwise chime in.
First off I must say thank you for giving me more helpful ideas to ask when I do finally opt to see the OB. At my 3rd m/c OB decided to do a panel for lupus, thyroid, bacterial, cmv, and clotting factors. All test came back normal the only test that came back slightly but however not totally out of range abnormal was my clotting times. I was taking longer to clot which is opposite of what she has thought. So thats why we were kind of left with the other option of karyotyping, and genetics. I will push for progesterone testing this next time. I am sure she will test if I ask. That is why I am kind of confused as to why I am m/c so many times. Nervous to see OB and want to postpone for as long as I can. However, as a nurse I know it is not a wise idea. UPDATE: I have not bled since the one event. Crossing fingers & legs
I sure hope so. This pregnancy would be a great surprise and happily welcomed by both sides. I only had that one event of spotting and then one prior to that but it have possibly been implantation bleeding it was 2 days before AF was due and then she never came.
Yes, I think lots of people spot around the time that AF is due because of implantation bleeding. Good luck!!!! Everything sounds very hopeful so far.
So bummed, I had spotting Saturday with dark red blood and light pink on Sunday. Feeling hopeless at this point.
I'm sorry, spotting is so scary! Have you called your OB yet?
Alissa, great info! Thanks for posting this. Also, this link might be useful as well.
Pednurse, you might also want to have your DH's sperm tested as well if you haven't already. I'm really sorry about the spotting. Please don't let this stress you out so much. Though, I know it's hard not to. Spotting does not automatically mean there's something wrong. You could have a subchorionic hematoma, an irritated cervix, hard bm or bd or any other number of things. When is your appointment with your OB? Also, were you referred to a Hematologist about your clotting issue? (((HUGS))) Sending you tons of sticky vibes!!
Jina (29 )
DS1 - 1/31/13 - My IVF Miracle and the love of my life!!
MC 8/24/10 @ 12w
MC 1/31/11 @ 11w6d
MC 8/18/11 @ 8w1d - ID Twins!
Alissa:No OB appointment yet. Still just waiting around I feel better with the unknown at this moment. And let life take its course and whatever is meant to be will. And if baby wants to stick it will. DH wants me to wait until I am 10 to 13 weeks until we see OB.
JKfm:DH has not been tested and neither have I for any genetics yet. We will hopefully attempt all blood tests first sometime within this year. Hoping we find the cause this way rather then it being a structural issue. I know spotting does not automatically mean m/c especially because I had a major bleed and clotting episode for 2 weeks with DS and thought I lost him only to have an u/s and find a healthy heart beat when I was 4 months pg. However, it is just hard extremely hard to stay so positive and think of other causes when I have had more losses then full term pregnancies. I have not made an OB appt and I am terrified to make one. Scared of what they will tell me, since most of the time it is always bad news. I just feel I should let nature take its course until I reach past the mark that I normally have my losses. My OB was the MD who ordered the clotting testing due to her thinking I may be clotting in my placentas however she did not find my blood test to be out of normal range but still prescribed me baby aspirin just to try.
THANK YOU ALL FOR POSITIVE VIBES. I STILL HAVE HOPE THIS BABY WILL STICK.