Day 1 post ER

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Day 1 post ER

Hi. I've been kind of hiding out but I've been lurking from time to time to see how everyone is doing. These past few weeks have been a roller coaster as my dad passed away suddenly the end of March when we were just in the first half of our IVF cycle. I was also starting my new job around the same time so was feeling pretty drained both emotionally and physically. We have gone on ahead with our IVF plan which I think has helped us and my family have something positive to focus on. We had the ER yesterday morning - 20 eggs, all mature. The clinic called today to say that 17 of them had fertilized. We have a D3 transfer tenatively scheduled (Fri) though we are hoping to make it to D5 (Sun) with some embies left to freeze. Since testing showed male infertility factor as the biggest issue, I'm hoping with ICSI we will have jumped that hurdle and the rest of the process will be much smoother from here.

Oh, and I was wondering if any of you had a progesterone protocol after ER and/or following ET? Since our clinic merged with another clinic, they have been updating a lot of their protocols (though my DH & I think it is a little odd that a lot of the protocol changes are in favor of the other clinic despite them having a slightly lower success rate than our clinic). One of the changes is from doing the IM progesterone injections after ER and then switching to suppositories after ET, and instead starting suppositiories right after ER. They gave us the option of doing either since they are still early on in the merge and we decided to go ahead with the IM injections first since we already had all the supplies (now that I'm sitting on my sore butt, I'm starting to question that decision). Any thoughts on one versus the other?

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Those are some great numbers!

As far as the PIO goes - I did the shots IM. However, next time I prefer to go with the suppositories. I talked to an RE about this for his opinion and this is what he said:

I have used both. I prefer the PIO
because I can monitor the level and feel good about the supplementation
with an objective number. I also know that all the data says that the
success rates are equal rather the support is vaginal vs PIO. The hormone
levels in the serum are lower with vaginal (but levels in the tissue are
higher: I just can't measure that). Bottom line: what I do is this:
discuss it with the patient and if they prefer vaginal supplementation I'm
fine with that ( for my FET's I use Crinone twice daily )

HTH!

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preg/m/c mentioned

I'm so sorry to hear of your dad's passing. I'm sure it's hard to be going through all of this with the stress of that. But like you said, it gives your family something to focus on. Now you have an angel looking over you.

With my cycles I did PIO after ER. I did get pregnant one cycle and if I am remembering correctly I had the option to switch to suppositories after my 1st u/s @ 7 wks. I stayed with the PIO because as my nurse said "if it's working, why mess with it." I didn't want something bad to happen and always wonder if it was because I changed up the progesterone. Unfortunately, I did m/c but not because of anything to do with the medications. Although, I did question if it was because they told me to stop the Vivelle dots. That had nothing to do with it though.

You had awesome numbers! How many are you thinking to transfer?

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If we do a D3 transfer probably 2 embryos. If we make it to D5 we will probably transfer just one depending on the embryo grading as we want to minimize our chance of multiples if possible. Our clinic has a 40% twin rate with

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So sorry for about your Dad...huge hugs!! So hard when it is sudden, I hope ou ahve been able to find some peace and comfort.

As for your ER...woot, woot!!! Great numbers, hope this is your month. I did PIO and will do it again this cycle. I personally like the shots. From what I have heard, the suppositories can be messy. I think all options do the trick, might just be preference.

Again goood luck and hope your 2ww goes by quick!! Make sure to keep us posted...

Rachel

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Clinic report today is 10 good quality embryos. So we will be moving forward with a D5 transfer on Sunday. Hope to transfer one good embryo and freeze the remainder just in case.

I think the PIO has been the most physically painful part of my IVF process. More so than the stinging Menopur injections, my botched IV, and the post ER discomfort. I woke up at 1am last night with my hips and butt just throbbing. I couldn't fall back asleep for several hours so finally I took 2 vicodin that I had prescribed for post ER pain. My friend told me today that I'm waddling when I walk. My heating pad is my best friend right now. I think similar to the "push" gift that some women ask for when pregnant, we should get an IVF gift from our significant others for all we go through Smile

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You're going to have an Easter baby!!!

What I did to get through the PIO was warm the syringe with the PIO in my hand before giving. After the injection I rubbed the site for a couple minutes. I also applied heat before and after the injection. I remember being so sore also. Hopefully it will all be worth it in the end.

Good luck on Sunday!!

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I did the same things as Meg - warmed it up in my hands for a few minutes to thin it out a bit and I iced the spot that was getting the injection. That way I was numb so it hurt way less.

Good luck!

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great fert. report! I agree with the PIO - i didn't do it on our fresh cycle cuz needles freak me out.... but they had me do the shots every 2 days ,along with suppost. when i did the FET.

As for the shots, i did similiar to what previous posters metnioned....heat!! Also, after the shot, and you have the heating pad on it, i would massage the area pretty well for about 10 mins

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My condolences for the loss of your father XTina - I also lost my dad a few years ago and know how tough it can be!

Best of luck with the transfer and hope you shall have some great news soon! God takes away sometimes but gives back in magical ways...

Sending lots of happy baby vibes your way..

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Thanks for the tips on PIO. I did some research and found a recommendation to lie flat on your stomach with your feet hanging over the edge of the couch or bed so you can totally relax the muscle during the shot - I don't know what position you all were using but I had been just bending over so maybe I wasn't relaxed.

I also started heating PIO in the syringe with my heating pad beforehand - I don't think DH's hands were warming it up enough.

Yes, I agree that massaging the area is key too. I was against having the area touched before because I thought it would hurt too much, but now I realize it really helps disseminate the oil.

So far so good, by adjusting our technique last few shots, my pain as improved tremendously. I haven't needed any pain meds the past two days, & no more waddling or sounding like an old lady when I go down and up from the couch or bed Biggrin

Clarinette - Thank you for your condolences & good luck to you too.

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Oh yes...bending over would make it hurt much worse since your muscle is tense as it's going in. I always laid flat on my stomach or side and relaxed as much as possible. I alternated sides and tried to find a spot that wasn't as sore each time. It gets hard to find non-sore spots as time goes on.

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I know I'm a little late jumping in... how did your transfer go??

I'm sorry to hear about your dad *HUGS* but I know he's smiling down on you, wishing you nothing but the best.

I have no recommendations or whatnot on the PIO... I've never had to do them (thank goodness). I hate needles so it just wasn't an option for me. I have a hard enough time with the sub-Q injections. I've used 2 different kinds of suppositories and while they are a bit messy at times, I'd much rather deal with that than needles Smile

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Transfer went well on Sunday. We transferred one pretty blastocyst. The 2nd blastocyst we had frozen and then they froze an additional 5 today after letting them further develop overnight so 6 snowflakes total. Other than a super full bladder things went smoothly. Even the RE commented on how full it was on U/S & had to cath me right after the transfer b/c I felt like I was going to burst. I've been resting at home since ET except for trip to my acupuncturist this morning. I'm having off and on mild cramping but try not to read too much into my symptoms as I've been fooled many cycles before. So overall taking it easy now while I can since I will be returning to work on Wednesday.

We are holding a community memorial for my dad two Saturdays from now. The day before ET, I was helping my mom scan photos for a slide show. It was pretty emotional seeing the pictures of my dad holding me and my siblings when we were younger and knowing I would not be able to take a picture of him holding his grandchild. It is comforting to know that I carry a part of him in my heart so he can be a part of this process.

Don't want to end on a sad note. I've officially switched from PIO to suppositories today - woo hoo!

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Congrats on being PUPO!! Glad you were able to switch to suppositories. When is your beta?

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So sorry for the feelings you are having... hugs!! I can only imagine how difficult it must be. Hope you know that we are here and if you feel like you need to share feel free to use this forum.

Hooray for your ET...glad it went well. I was wondering why you only transferred 1, is that your clinic policy? Rest up and keep us updated on your 2 ww!!

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My beta is Tues May 3rd.

Haven't decided if I want to home test prior to then. Out of curiosity I took a HPT to see if the trigger shot was still in my system b/c I got a false positive 8 days after my IUI in January. This test was completely negative so at least if I got a BFP it would likely be the real thing. On the otherhand, I don't know if I would be more upset to know it was probably negative before getting the clinic results or hearing it's negative over the phone first.

reb2591020- Our RE offered to let us transfer up to two but DH & I made the decision to transfer only one b/c we had a really good blastocyst, our clinic has high success rate for my age group (about 63%) and high multiples rate when more than one embryo is transferred (around 40%). Knowing that we would likely have some to freeze also made us okay with transferring just one this cycle. With all the extra medical intervention we've needed TTC, I really want to go with a more natural childbirth if possible and I think this would be more difficult to achieve if I became pregnant with twins. But maybe in future cycles we will transfer more, you never know. We were getting some gentle pushing from my mom and my best friend to transfer two, but we stuck to our plan.

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You have to do what is right for you. Good for you and hubs to stand strong. I hope this is your month!!

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YEAH for a great transfer! Congrats on being PUPO! I hope this is it for you.

Good for you for sticking to your plan... I know it's hard sometimes but we are the only ones that know what's right for our situation. *HUGS*