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  1. #1
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    Default Day 1 post ER

    Hi. I've been kind of hiding out but I've been lurking from time to time to see how everyone is doing. These past few weeks have been a roller coaster as my dad passed away suddenly the end of March when we were just in the first half of our IVF cycle. I was also starting my new job around the same time so was feeling pretty drained both emotionally and physically. We have gone on ahead with our IVF plan which I think has helped us and my family have something positive to focus on. We had the ER yesterday morning - 20 eggs, all mature. The clinic called today to say that 17 of them had fertilized. We have a D3 transfer tenatively scheduled (Fri) though we are hoping to make it to D5 (Sun) with some embies left to freeze. Since testing showed male infertility factor as the biggest issue, I'm hoping with ICSI we will have jumped that hurdle and the rest of the process will be much smoother from here.

    Oh, and I was wondering if any of you had a progesterone protocol after ER and/or following ET? Since our clinic merged with another clinic, they have been updating a lot of their protocols (though my DH & I think it is a little odd that a lot of the protocol changes are in favor of the other clinic despite them having a slightly lower success rate than our clinic). One of the changes is from doing the IM progesterone injections after ER and then switching to suppositories after ET, and instead starting suppositiories right after ER. They gave us the option of doing either since they are still early on in the merge and we decided to go ahead with the IM injections first since we already had all the supplies (now that I'm sitting on my sore butt, I'm starting to question that decision). Any thoughts on one versus the other?

  2. #2
    Posting Addict Jenn0113's Avatar
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    Those are some great numbers!

    As far as the PIO goes - I did the shots IM. However, next time I prefer to go with the suppositories. I talked to an RE about this for his opinion and this is what he said:

    I have used both. I prefer the PIO
    because I can monitor the level and feel good about the supplementation
    with an objective number. I also know that all the data says that the
    success rates are equal rather the support is vaginal vs PIO. The hormone
    levels in the serum are lower with vaginal (but levels in the tissue are
    higher: I just can't measure that). Bottom line: what I do is this:
    discuss it with the patient and if they prefer vaginal supplementation I'm
    fine with that ( for my FET's I use Crinone twice daily )

    HTH!
    Jenn & Jus 1.13.06
    Deacon: 11.11.08
    Kara: 12.27.11


  3. #3
    Community Host meggyrn's Avatar
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    Default preg/m/c mentioned

    I'm so sorry to hear of your dad's passing. I'm sure it's hard to be going through all of this with the stress of that. But like you said, it gives your family something to focus on. Now you have an angel looking over you.

    With my cycles I did PIO after ER. I did get pregnant one cycle and if I am remembering correctly I had the option to switch to suppositories after my 1st u/s @ 7 wks. I stayed with the PIO because as my nurse said "if it's working, why mess with it." I didn't want something bad to happen and always wonder if it was because I changed up the progesterone. Unfortunately, I did m/c but not because of anything to do with the medications. Although, I did question if it was because they told me to stop the Vivelle dots. That had nothing to do with it though.

    You had awesome numbers! How many are you thinking to transfer?

    Meg-30 DH-42

    2 IUI's-BFN
    IVF #1-cancelled d/t embryos arresting before transfer (3/09)
    IVF #2-BFP 9wks-7/30/09 (6/09)
    IVF #3-BFN (5/10)

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    If we do a D3 transfer probably 2 embryos. If we make it to D5 we will probably transfer just one depending on the embryo grading as we want to minimize our chance of multiples if possible. Our clinic has a 40% twin rate with <35 year old group when more than one embryo is transferred.

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    So sorry for about your Dad...huge hugs!! So hard when it is sudden, I hope ou ahve been able to find some peace and comfort.

    As for your ER...woot, woot!!! Great numbers, hope this is your month. I did PIO and will do it again this cycle. I personally like the shots. From what I have heard, the suppositories can be messy. I think all options do the trick, might just be preference.

    Again goood luck and hope your 2ww goes by quick!! Make sure to keep us posted...

    Rachel

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    Clinic report today is 10 good quality embryos. So we will be moving forward with a D5 transfer on Sunday. Hope to transfer one good embryo and freeze the remainder just in case.

    I think the PIO has been the most physically painful part of my IVF process. More so than the stinging Menopur injections, my botched IV, and the post ER discomfort. I woke up at 1am last night with my hips and butt just throbbing. I couldn't fall back asleep for several hours so finally I took 2 vicodin that I had prescribed for post ER pain. My friend told me today that I'm waddling when I walk. My heating pad is my best friend right now. I think similar to the "push" gift that some women ask for when pregnant, we should get an IVF gift from our significant others for all we go through

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    Community Host meggyrn's Avatar
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    You're going to have an Easter baby!!!

    What I did to get through the PIO was warm the syringe with the PIO in my hand before giving. After the injection I rubbed the site for a couple minutes. I also applied heat before and after the injection. I remember being so sore also. Hopefully it will all be worth it in the end.

    Good luck on Sunday!!

    Meg-30 DH-42

    2 IUI's-BFN
    IVF #1-cancelled d/t embryos arresting before transfer (3/09)
    IVF #2-BFP 9wks-7/30/09 (6/09)
    IVF #3-BFN (5/10)

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    Posting Addict Jenn0113's Avatar
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    I did the same things as Meg - warmed it up in my hands for a few minutes to thin it out a bit and I iced the spot that was getting the injection. That way I was numb so it hurt way less.

    Good luck!
    Jenn & Jus 1.13.06
    Deacon: 11.11.08
    Kara: 12.27.11


  9. #9
    Mega Poster grovey2's Avatar
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    great fert. report! I agree with the PIO - i didn't do it on our fresh cycle cuz needles freak me out.... but they had me do the shots every 2 days ,along with suppost. when i did the FET.

    As for the shots, i did similiar to what previous posters metnioned....heat!! Also, after the shot, and you have the heating pad on it, i would massage the area pretty well for about 10 mins

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    My condolences for the loss of your father XTina - I also lost my dad a few years ago and know how tough it can be!

    Best of luck with the transfer and hope you shall have some great news soon! God takes away sometimes but gives back in magical ways...

    Sending lots of happy baby vibes your way..

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